AKT1 and small cell lung carcinoma: Treatment with MK-2206 or LY294002 was shown to reduce the phosphorylation of AKT(T308) and AKT(S473), as previously reported (Additional file 1: Figure S1A); however, the survival of the 13 SCLC cells lines was unaffected at the concentration of 1.0 μM (Additional file 1: Figure S1B, C).