AFP alpha-fetoprotein, ALPlat index platelet count + 90 × albumin, ALT alanine aminotransferase, APRI AST-to-platelet ratio index, AST asparate aminotransferase, BCLC Barcelona Clinic Liver Cancer, BMI body mass index, CRP C-reactive protein, DCP des-γ-carboxyprothrombin, FIB-4 fibrosis-4, HBV hepatitis B virus, HCV hepatitis C virus, ICG-R15 indocyanine green dye retention rate at 15 min, MELD model for end-stage liver disease, PALBI platelet-albumin-bilirubin, PHLF posthepatectomy liver failure, PT prothrombin time, TNM tumor, node, metastasis *P < 0.05 and **P < 0.001. The gene discussed is AFP; the disease is liver disorder.