As shown in Fig. 2a, the tumors associated with high expression of APOBEC3B and poor OS were ACC (P < 0.001), LGG (P < 0.001), LIHC (P = 0.03) and UVM (P = 0.032) within the TCGA project In the DFS analysis (Fig. 2b). The gene discussed is APOBEC3B; the disease is adrenal cortex carcinoma.