With every 10% increase in standardized urine NGAL [OR 2.69, 95% CI (1.56, 4.63), p < 0.001], and standardized serum creatinine [OR 2.69 95% CI (1.54, 4.69), p < 0.001], the odds of progression to CKD increased by 9.8%. The gene discussed is LCN2; the disease is chronic kidney disease.