In this first of its kind prospective cohort study of patients with CA-AKI from a developing country, we show that serum MIOX, urine NGAL, serum creatinine and uPCR at the time of discharge were independently associated with progression to CKD from CA-AKI after adjusting for gender, age, hypertension, diabetes, requirement of renal replacement therapy and duration of hospitalization. This evidence concerns the gene LCN2 and acute kidney injury.