COPD-specific genes (CORIN, SELL, SH3PXD2B) and LUAD-specific critical genes (ASPM, CENPF, MAD2L1, TOP2A, CDKN2A, ELF3, IGFBP2) were expressed at higher levels in comparison to normal controls. This evidence concerns the gene CORIN and chronic obstructive pulmonary disease.