CDKN2A and neoplasm: Notably, locus 17p13.1 includes TP53. The most common focal copy number aberrations identified in WGS samples included: (i) amplification involving a fragment of 8q24.21 and affecting MYC (n = 4), (ii) homozygous deletion involving a fragment of 22q12.2 affecting TTC28 (n = 7)—which inhibits tumor cell growth by interacting with TP5317, and (iii) deletion involving a fragment of 9p21.3 directly affecting tumor suppressor CDKN2A (n = 7; homozygous deletion in six samples, and deletion of one copy in one sample).