HECTD3 and neoplasm: We detected the number of GFP-labeled tumor cells in the lungs in a time course experiment and found that, at 10 min after injection, the number of GFP-positive tumor cells in the lungs of Hectd3−/− mice was almost equal to that in WT mice, but significantly decreased at 10 h and 20 h after injection (Fig. 6d, e).