Pearson's correlation analysis confirmed that PTEN expression was negatively interrelated with miR-494-3p expression (R2 = 0.3848, p < 0.001), but positively correlated with circ_0000317 expression in NSCLC tissues (R2 = 0.4104, p < 0.001) (Fig. 4C). This evidence concerns the gene PTEN and non-small cell lung carcinoma.