To further study whether circ_0000317 impacts NSCLC progression via modulating miR-494-3p/PTEN axis, the authors transfected pcDNA3.1-circ_0000317, pcDNA3.1-circ_0000317 + miR-control, and pcDNA3.1-circ_0000317 + miR-494-3p mimics in PC9 and A549 cells, respectively, followed by function compensation experiments (Fig. 5A-B). Here, PTEN is linked to non-small cell lung carcinoma.