To explore whether expressions of PD-L1, CSF1R, and IFN-γ are correlated with CD11c expression in human cancer patients, data mining analyses were performed in human Lung Adenocarcinoma (LUAD), Lung Squamous Cell Carcinoma (LUSC), and Skin Cutaneous Melanoma (SKCM) samples of the TCGA database. The gene discussed is CD274; the disease is lung adenocarcinoma.