For instance, one institution designed a program that screened for severe (BG > 250 mg/dL at least once) or persistent hyperglycemia (> 180 mg/dL at least twice 3 h apart) in those with diabetes and stress hyperglycemia on only sliding scale insulin, and for type 1 diabetes on sliding scale insulin alone [29]. This evidence concerns the gene INS and type 1 diabetes mellitus.