Recently, several potential autoantigens have been reported in the context of IgG4-RD including type 1 AIP: prohibitin [99], annexin A11 [100], laminin 511-E8 [101], galectin-3 [102] and anti-IL-1 receptor antagonist (IL-1RA) [103]. Here, IL1R1 is linked to immunoglobulin G4-related sclerosing disease.