The patient was a 73-year-old man with a medical history of surgical treatment for esophageal cancer (15 years prior, squamous cell carcinoma, pT1 {LPM} N0 M0, pathological stage 0) and colon cancer (five years prior, adenocarcinoma, pT1 {SM} N0 M0, pathological stage 1, immunohistochemistry staining: cytokeratin {CK} 7 {-}, CK 20 {+}, thyroid transcription factor-1 {TTF-1} {-}, and caudal type homeobox 2 {CDX-2} {+}). The gene discussed is CDX2; the disease is malignant colon neoplasm.