MMP9 and cancer: KEGG pathway enrichment analysis showed that EGR2, EGR3, HLA-A, MMP9, VEGFA, and TP65 genes are involved in microRNAs in cancer, viral carcinogenesis, relaxin signaling pathway, hepatitis B, fluid shear stress, and atherosclerosis (Figure 2(c)), suggesting that microRNAs, viruses, etc., may affect the efficacy of neoadjuvant chemotherapy.