APACE: Advantageous Predictors of Acute Coronary Syndromes Evaluation Study; AMI: Acute myocardial infarction (patients with ST-segment elevation myocardial infarction not excluded in study sample); NSTEMI: Non-ST-segment elevation myocardial infarction; SD: Standard deviation; IQR: Interquartile range; e-GFR: Estimated glomerular filtration rate; hs-cTnT: Highly sensitive cardiac troponin T assay; s-cTnI: Sensitive-cardiac troponin I assay; hs-cTnI: Highly sensitive cardiac troponin I assay; cTnT: Conventional troponin T assay. The gene discussed is TNNI3; the disease is acute coronary syndrome.