SPP1 and hepatocellular carcinoma: As shown in Figure 3(d), there were higher expression levels of LPCAT1 (p = 3.46e − 39), SPP1 (p = 1.84e − 22), KPNA2 (p = 1.18e − 72), and KIF2C (p = 2.33e − 51) and a lower expression level of FMO3 (p = 1.63e − 29) in HCC tissues than in the matched paraneoplastic tissues.