The general recommendation is that CKD screening in individuals with diabetes should begin within five years after the diagnosis of T1DM and at the diagnosis of T2DM, which should include measuring urinary albumin-to-creatinine ratio (uACR) to detect microalbuminuria and serum creatinine (and/or cystatin C) for the calculation of eGFR [37] (Table 2). Here, CST3 is linked to chronic kidney disease.