The protective role of SIRT1 was also observed in several infectious diseases, including infections of viruses (e.g. respiratory syncytial virus and dengue virus), bacteria (e.g. Pseudomonas aeruginosa and Helicobacter pylori) and protozoan parasites (e.g. Toxoplasma gondii, Trypanosoma cruzi and Cryptosporidium parvum) [34–40]. Here, SIRT1 is linked to infection.