The percentages of these drug-resistant pathogens in the SS-CRS group were MRSA (5.7%), MDRAB (2.9%), CRPA (0%) and ESBL-KP (0%) and those in the non-SS-CRS group were MRSA (1.7%), MDRAB (0.5%), CRPA (0.06%) and ESBL-KP (0.03%) (Fig. 5). The gene discussed is NPPA; the disease is congenital rubella syndrome.