PTEN and gastric cancer: Pan et al. reported correlation and interaction among VDR, phosphatase, and tensin homolog deleted on chromosome 10 (PTEN), and epigenetic modifiers such as 5-aza-2-deoxycytidine, trichostatin A (TSA), sodium butyrate upon binding of Calcitriol to VDR may be able to enhance the apoptosis in human GC cells [29].