APOC3 and metabolic dysfunction-associated steatotic liver disease: On the contrary, genes LPL, MMP9, APOC2, APOC3, APOA4, ZEB2, TGFBI, MMP2 which were all upregulated in NAFLD samples were also upregulated only in obese iPSCs in both nontreated and palmitate treated cells, particularly on day 13 (Fig. S2B and Supplementary file 17).