HCRT and Autoimmunity: In one case, a TRAJ24 clone isolated from a narcoleptic patient showed elevated TCR reactivity toward HCRT87–97-NH2 when transfected in Jurkat 76 (J76) cells, thus implying a role for TRAJ24 reactivity toward DQ0602-HCRT in narcolepsy autoimmunity (39).