Each CPP was conjugated via copper(I)-catalyzed click chemistry to the C terminus of an 18-mer-long peptide (gp10020–38, hereafter gp100) encompassing the H-2Db–restricted epitope EGPRNQDWL (gp10025–33) of the melanoma tumor-associated antigen (Fig. 1A) (50, 51). The gene discussed is PMEL; the disease is melanoma.