APC and cancer: β-catenin binds transducin beta-like protein 1 (TBL1/TBLR1), and this complex stimulates the expression of several Wnt/APC/β-catenin pathway target genes, including proliferative factors, such as S100A4 or collagen triple helix repeat containing-1 (CTHRC1), identified as cancer-related proteins[29, 30, 31].