It is known that beta-catenin is an important component of the epithelial adherens junction together with E-cadherin, cytoplasmic p120-catenins and α-catenins: dynamic changes of the adherens junction structure appear to underlie the initiation and progression of acute pancreatitis (AP) as well as the following repair mechanisms [78]. The gene discussed is CTNND1; the disease is acute pancreatitis.