WWTR1 and neoplasm: In a chemical two‐stage skin carcinogenesis mouse model, which involves tumor initiation by the application of a sub‐carcinogenic dose of a carcinogen (e.g. 7,12‐dimethylbenz[a]‐anthracene (DMBA)) and subsequent tumour development by repeated treatment with the tumour‐promoting agent 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA),169 YAP/TAZ were also shown to be essential for tumor development.12