CXCL8 and systemic lupus erythematosus: However, when we compared the cytokines among the controls, LN, and non-LN SLE patients, 12 cytokines, including IL-8, differed significantly between controls and LN SLE patients (Fig. S12; Padj < 0.05), and no cytokines differed significantly between controls and non-LN SLE patients.