Infection with both strains of Coxiella also repressed expression of several transcripts at 8 h, including genes with roles in cell adhesion and migration (sorbs3, loxl3, arhgap6, tens1, plxnc1), lipid metabolism (agmo, st6gal1), and innate immune signaling (irf4, lifr, cxcr4). Here, IRF4 is linked to infection.