Infection with both strains of Coxiella also repressed expression of several transcripts at 8 h, including genes with roles in cell adhesion and migration (sorbs3, loxl3, arhgap6, tens1, plxnc1), lipid metabolism (agmo, st6gal1), and innate immune signaling (irf4, lifr, cxcr4). The gene discussed is PLXNC1; the disease is infection.