CD274 and bacterial infectious disease: Based on prior reports of host susceptibility factors for bacterial infection (21, –, 24), rAM expression of several potentially relevant genes was altered post-IAV infection, including pathogen-related receptors (i.e., Cd36 and Ptafr), interferon induced genes (i.e., Stat1 and If204), and inflammatory response-related genes (i.e., Cd274, Ptger4, Litaf, Tmem173, Fcgr1, and Cybb) (Fig. 2B).