In multivariate analysis, the variables that were found to be statistically significantly associated with postoperative AKI in univariate analysis were increased CIMT (p = 0.005), pre-operative CRP (p = 0.001), ESR (p = 0.005), NLR (p = 0.0001) and PLR (p = 0.0001); increased postoperative seventh-day CRP (p = 0.04), postoperative firstday PLR (p = 0.0001), postoperative seventh-day ESR (p= 0.02), and intubation time (p = 0.02). The gene discussed is CRP; the disease is acute kidney injury.