It has also been shown that KRG assumption produced in IFG, IGT, and T2DM patients a significant decrease in serum insulin levels at 0 min (−0.90 μIU/dl, −13.40%, p = .024) and 30 min (−7.67 μIU/dl, −29.00%, p = .007) with a tendency to lowering at 60 min (−7.50 μIU/dl, −13.40%, p = .070) and 120 min (−8.24 μIU/dl, −21.00%, p = .070) during OGTT respect to baseline. The gene discussed is INS; the disease is type 2 diabetes mellitus.