It also needs to be further investigated whether hypoxia induces altered FSP-27 expression, to what extent it is involved in the regulation of FSP-27 expression, what role HIF-1 and HIG-2 play in the altered FSP-27 expression, and whether FSP-27 expression in tumor cells correlates with the availability of tumor cells to lipids. This evidence concerns the gene HIF1A and neoplasm.