SMARCB1 and familial rhabdoid tumor: Patient 1 had a heterozygous frameshift variant in SMARCB1 (p.Pro215Leufs*14), while patients 2 and 3 had a large deletion (>1 Mb) of chr22q11, a region which includes the SMARCB1 gene, present in germline comparator tissue, thus confirming a diagnosis of rhabdoid tumor predisposition syndrome for all three.