To clarify the correlation between 7 PRGs (BTK, CASP5, EEF2K, GZMA, NR1H2, RIPK3, and SDHB) derived from LASSO Cox regression analysis and immune infiltration in COAD, we applied Tumor Immune Estimation Resource (TIMER) database on these genes. The gene discussed is GZMA; the disease is neoplasm.