ZNF217 and esophagitis: Similarly, ZNF217 amplification was associated with severe pneumonitis and esophagitis (grade 3 or higher; OR=7.5 [95% CI, 2.0-28.0], P=0.003), as well as severe radiation-induced pneumonitis (OR=4.9 [95% CI, 1.3-18.2], P=0.02).