FOXC2 and lung cancer: Another study investigating the epigenetic effects of resveratrol in lung cancer identified a signaling cascade, resveratrol|miRNA-520h|PP2A/C|Akt|NF-κB|FOXC2, in which resveratrol inhibits both gene and protein expression of the transcriptional factor FOXC2 by downregulating the oncogenic miRNA-520h and the downstream signaling cascade (Yu et al., 2013).