APOE and intracerebral hemorrhage: Table 2 shows the odds ratios (ORs) for the SVD markers on MRI depending on the APOE genotype. Only two patients with SCI had APOE ε2/2 and both had the lowest dichotomized white matter hyperintensity and enlarged perivascular score, had no CMBs, large or lacunar infarctions, intracerebral hemorrhage, or cortical superficial siderosis.