As shown in the bubble chart, B cells, CD4+ memory T cells, natural killer (NK) T cells, activated CD4+ memory T cells, Th1 CD4+ T cells, Th2 CD4+ T cells, CD8+ T cells, and cancer-associated fibroblasts were positively correlated with risk scores, while in the XCELL and EPIC platforms, macrophages were negatively correlated with risk score (all p < 0.05) (Figure 6B). The gene discussed is CD4; the disease is cancer.