Heterozygous amplifications of ETS2 and CDK6 in TGCT; CDK6 in GBM; E2F1 and ID1 in rectum adenocarcinoma (READ); and SP1, CDK4, and MDM2 in ACC were all greater than 70% (Figure 7D). The gene discussed is E2F1; the disease is adrenal cortex carcinoma.