CBS and Alzheimer disease: On the other hand, CBS phenotype may be the predominant clinical picture of various pathologies other than CBD in addition to PSP (PSP-CBS), including PiD (PiD-CBS), Alzheimer's disease pathology (AD-CBS), transactive response DNA binding protein 43 kDa (TDP-43) (TDP-CBS), and rarely LBD, GGT, vascular pathology, or even sporadic Creutzfeldt- Jacob disease (sCJD) (25, 32, 118–121).