It is important to note that exclusion criteria exist for both categories and include the evidence of biomarkers to exclude Alzheimer's disease [AD; such as amyloid positron emission tomography (PET) or tau and amyloid in cerebrospinal fluid (CSF)], structural lesion suggestive of focal causes, granulin mutation or reduced plasma progranulin levels, TDP-43 mutations, fused in sarcoma (FUS) mutations, evidence of Lewy body disease (LBD), multiple system atrophy (MSA), amyotrophic lateral sclerosis, or svPPA (24). This evidence concerns the gene GRN and Lewy body dementia.