A more posterior pattern of atrophy has instead been associated with other genetic forms of MND—mostly, related to C9orf72 pathologic expansions (32, 72, 73)—, leading to the hypothesis that genetic mutations may promote neurodegeneration also in areas that are not typically involved in MND, possibly due to an accelerated neurodegenerative process (32, 72, 73). This evidence concerns the gene C9orf72 and mild neurocognitive disorder.