Whereas, no substantial binding to tubulin was observed for the MJFR1 antibody, tubulin cross-reactivity of the LB509 antibody, observed in this study, might be linked to the fact that this antibody was raised against Lewy bodies purified from the brains of patients with DLB, which contain not only aSyn, but also a number of other proteins, such as β- and γ-synucleins, tubulin, ubiquitin, tau, and neurofilament (6, 60). Here, MAPT is linked to Lewy body dementia.