E0771 cells lack surface CXCR4, a widely expressed chemokine receptor involved in breast cancer survival and metastasis (43), but retains high surface levels of the “don’t eat me signal” CD47 (44), implicated in the escape of CTC from systemic macrophage and neutrophil-mediated phagocytosis (44) (Supplementary Figure 3). This evidence concerns the gene CXCR4 and breast carcinoma.