The primary breast tumors of either control or ICAM-1 KO OVA-expressing E0771 cells were implanted in syngeneic mice; 3 days later, OT-I CTLs were i.v.-injected into these mice, and the tumor size was monitored from day 12 to day 16 postinitial tumor implantation. Here, ICAM1 is linked to breast neoplasm.