For this reason, we implanted a very low number of control and ICAM-1 KO E0771 cells embedded in Matrigel (45) in the mammary fat pad of syngeneic C57BL/6 female mice (i.e., 1 × 103 cells) and followed tumor growth 13, 17, and 21 days after implantation (Figure 1C). The gene discussed is ICAM1; the disease is neoplasm.