They also had a lower eGFR, higher UPCR, higher rates of pyuria, hematuria, anemia, neutropenia, and lymphopenia, higher inflammatory marker levels, lower C3 levels, higher anti-dsDNA Ab levels, higher SLEDAI-2K scores, and higher urine usCD163/creatinine ratio (p < 0.05). The gene discussed is C3; the disease is anemia (phenotype).