Serum-soluble CD163 (29), monocyte chemoattractant protein-1 (MCP-1), neutrophil gelatinase-associated lipocalin (NGAL), TNF-like weak inducer of apoptosis (TWEAK), and vascular cell adhesion molecule-1 (VCAM) are new biomarkers of SLE disease activity (30). Here, TNFSF12 is linked to systemic lupus erythematosus.