CD8A and lymphopenia: Our study suggests that some lymphocyte parameters might be useful to physicians to better characterize patients at hospital admission; in particular, identification of patients with potential mild (with low levels of T-cell activation) or very serious (with profound CD8+ T-cell lymphopenia, a high level of CD4+ and CD8+ T-cell activation and a high level of CD8+ T-cell senescence) evolution of the pathology could be helpful in order to treat them earlier and more appropriately.