Expression of genes related to proliferation of RA-FLSs, including spectrin repeat-containing nuclear envelope 1 (SYNE1), Fc receptor-like 2 (FCRL2), PYD (pyrin domain)-containing 1 (PYDC1), cell division cycle 45 homolog (CDC45), signal transducer and activator of transcription 5B (STAT5B), and interferon regulatory factor 4 (IRF4), was increased after TL1A stimulation (70). This evidence concerns the gene SYNE1 and rheumatoid arthritis.