IL-1α was lower in AN patients or patients with obesity with or without BED than in healthy controls, while IL-1α was not influenced by BMI or depression.IL-10 was higher in AN than in healthy controls. IL-10 was lower in obesity groups compared to normal weight group.IFN-γ was higher in AN patients compared to healthy controls, and BED and obesity without BED individuals.Night-eating was positively associated with IL-8.IL-10 was positively related to post-dinner eating and negatively related to sweet eating. The gene discussed is CXCL8; the disease is obesity due to melanocortin 4 receptor deficiency.