IFNA1 and infection: We infected these cells cultures in vitro with a Renilla Luciferase expressing X4-tropic HIVNL4.3. In addition, the infected cell cultures were directly stimulated with IFNα2, IFNα14, or IFNβ and the IFN-mediated effects on viral loads, immune cell activation, as well as cytokine and chemokine production were analyzed four days post infection (dpi).