IL6 and Autoimmunity: The cytokine interleukin-6 (IL-6) is a key contributor to T cell dysregulation in the context of autoimmunity, promoting pro-inflammatory T cell lineages, including T helper 17 cells (Th17) and T follicular helper cells (Tfh), inhibiting regulatory T cell (Treg) lineages (1, 2), as well as supporting the proliferative and survival capacities of pathogenic T cells (3, 4).