STAT4 and systemic lupus erythematosus: Previous studies found many target genes related to SLE risk, such as signal transducer and activator of transcription 4 (STAT4), death-associated protein 1 (DAP1), mannose binding lectin 2 (MAB2), prostaglandins E2 (PGE2), and PIN2/TERF1-interacting telomerase inhibitor 1 (PINX1) (3–8).