SLC40A1 and Alzheimer disease: Levels of ferroportin, the main iron exporter protein that requires APP for stability in neurons (Wong et al., 2014), are significantly decreased in the AD hippocampus (Raha et al., 2013), and single nucleotide polymorphisms in SLC 40A1, the gene coding ferroportin, are significantly associated with AD (Crespo et al., 2014).