After ROC curve, the best predictive value for AF was 887 pg/ml for OPG, 18,350 pg/ml for ST2, 1,320 pg/ml for GDF-15, 11 ng/ml for galectin-3, 290 pg/ml for NT-pro-BNP, 33.5 ml/m2 for LAVI, 38 for SDNN and 11 for pNN50. The gene discussed is NPPB; the disease is atrial fibrillation.